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Cannabis, also known as bud among other names, is a carcinogenic drug from the Cannabis plant intended for recreational or medical use. The key psychoactive part of cannabis is tetrahydrocannabinol (THC); one of 483 known chemicals in the plant, including at least 65 other cannabinoids. Cannabis may be used by smoking, vaporizing, in food, or as an infusion.

Cannabis is often used because of its mental and physical effects, such as a "high" or "stoned" sense, a general change in perception, euphoria (increased mood), along with an increase in appetite. Onset of consequences is within minutes when smoked, and about 30 to 60 minutes consumed and once cooked. They last for between two and six hours. Short-term side effects may include a reduction in short-term memory, dry skin, impaired motor skills, reddish eyes, and feelings of paranoia or anxiety. Long-term side effects could include dependence, decreased mental ability in individuals who began as teenagers, and behavioral problems in children whose mothers used cannabis during pregnancy. Studies have found a strong relation between cannabis use and the risk of psychosis, though the cause-and-effect connection is debated.

Cannabis is mostly used recreationally or as a medicinal drug, though it might also be used for religious or spiritual purposes. In 2013, between 128 and 232 million people used cannabis (2.7% to 4.9 percent of their international population between the ages of 15 and 65). In 2015, 43 percent of Americans had used cannabis, which increased to 51% in 2016. About 12% have used it at the last year, and 7.3% have used it within the last month. This makes it the most frequently used illegal drug both on earth and the United States.

The oldest recorded uses date from the 3rd century BC. Since the early 20th century, cannabis was subject to legal restrictions. The ownership, use, and sale of cannabis is illegal in many countries of the planet. Medical cannabis refers to the physician-recommended usage of cannabis, which is taking place in Canada, Belgium, Australia, the Netherlands, Germany, Spain, and 23 U.S. nations. Cannabis use began to become popular in the U.S. in the 1970s. Support for legalization has increased in the USA and several U.S. countries have legalized recreational or medical use.

In December 2012, the U.S. state of Washington became the first nation to officially legalize cannabis at a state law (Washington Initiative 502) (but nevertheless prohibited by federal law), together with the state of Colorado after close behind (Colorado Amendment 64). [200] On January 1, 2013, the primary marijuana "club" for private marijuana smoking (no buying or selling, however) was permitted for the first time in Colorado. The California Supreme Court determined in May 2013 that local governments can prohibit medical marijuana dispensaries despite a state law in California that allows the use of cannabis for medical purposes. At least 180 cities around California have enacted bans in recent years.

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